Daniel Menezes-Souza Selected Research

Leishmaniasis

8/2022	Mapping linear B-cell epitopes of the Tryparedoxin Peroxidase and its implications in the serological diagnosis of tegumentary leishmaniasis.
6/2022	Development of an immunogen containing CD4+/CD8+ T-cell epitopes for the prophylaxis of tegumentary leishmaniasis.
9/2021	Development of a chimeric protein based on a proteomic approach for the serological diagnosis of human tegumentary leishmaniasis.
11/2019	Immunodiagnosis of human and canine visceral leishmaniasis using recombinant Leishmania infantum Prohibitin protein and a synthetic peptide containing its conformational B-cell epitope.
4/2019	Leishmania infantum β-Tubulin Identified by Reverse Engineering Technology through Phage Display Applied as Theranostic Marker for Human Visceral Leishmaniasis.
1/2019	A biomarker for tegumentary and visceral leishmaniasis based on a recombinant Leishmania hypothetical protein.
1/2019	High-through identification of T cell-specific phage-exposed mimotopes using PBMCs from tegumentary leishmaniasis patients and their use as vaccine candidates against Leishmania amazonensis infection.
12/2018	Diagnostic application of recombinant Leishmania proteins and evaluation of their in vitro immunogenicity after stimulation of immune cells collected from tegumentary leishmaniasis patients and healthy individuals.
11/2018	A Leishmania hypothetical protein-containing liposome-based formulation is highly immunogenic and induces protection against visceral leishmaniasis.
6/2018	Serological diagnosis and prognostic of tegumentary and visceral leishmaniasis using a conserved Leishmania hypothetical protein.

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Daniel Menezes-Souza Research Topics

Disease

38	Visceral Leishmaniasis (Kala Azar) 02/2022 - 01/2012
30	Infections 07/2022 - 07/2013
29	Leishmaniasis 08/2022 - 12/2013
7	Chagas Disease (American Trypanosomiasis) 07/2018 - 01/2014
2	Inflammation (Inflammations) 12/2021 - 04/2021
2	Communicable Diseases (Infectious Diseases) 07/2018 - 01/2018
1	Drug-Related Side Effects and Adverse Reactions 02/2022
1	Necrosis 01/2019
1	Chagas Cardiomyopathy 07/2018
1	Asymptomatic Infections 12/2017
1	Babesiosis (Piroplasmosis) 08/2017
1	Ehrlichiosis 08/2017
1	Neglected Diseases 06/2016
1	Dog Diseases (Disease, Canine) 02/2015
1	Parasitic Diseases (Parasitic Disease) 07/2014
1	Fascioliasis 07/2013
1	Asymptomatic Diseases 04/2011

Drug/Important Bio-Agent (IBA)

35	Proteins (Proteins, Gene)FDA Link 01/2022 - 04/2014
20	VaccinesIBA 01/2019 - 12/2013
12	AntigensIBA 08/2022 - 01/2014
9	Peptides (Polypeptides)IBA 11/2019 - 07/2014
7	MicellesIBA 07/2022 - 10/2016
6	B-Lymphocyte Epitopes (B-Cell Epitope)IBA 08/2022 - 01/2014
6	Recombinant ProteinsIBA 01/2020 - 01/2015
6	AntibodiesIBA 01/2019 - 11/2015
6	EpitopesIBA 01/2017 - 01/2014
5	Interleukin-4 (Interleukin 4)IBA 04/2021 - 07/2013
4	Interleukin-12 (IL 12)IBA 04/2021 - 10/2018
4	CytokinesIBA 04/2021 - 07/2013
4	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2020 - 01/2018
4	Immunoglobulin G (IgG)IBA 01/2020 - 01/2016
4	Interleukin-10 (Interleukin 10)IBA 01/2019 - 07/2013
3	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 06/2022 - 07/2015
3	SaponinsIBA 01/2018 - 06/2016
2	NaphthoquinonesIBA 02/2022 - 01/2019
2	ChemokinesIBA 12/2021 - 12/2013
2	NitritesIBA 01/2020 - 01/2018
2	DNA VaccinesIBA 01/2020 - 01/2018
2	Pyridoxal KinaseIBA 01/2020 - 01/2020
2	ProhibitinsIBA 11/2019 - 01/2018
2	Biological ProductsIBA 04/2019 - 10/2016
2	Biomarkers (Surrogate Marker)IBA 01/2019 - 12/2018
2	Liposomes (Liposome)IBA 11/2018 - 02/2015
2	Recombinant Fusion ProteinsIBA 10/2018 - 01/2017
2	InterferonsIBA 10/2018 - 01/2018
2	Amphotericin B (Amphotericin)FDA LinkGeneric 03/2018 - 10/2016
2	InterleukinsIBA 01/2018 - 07/2013
2	EnzymesIBA 04/2017 - 07/2014
2	ImmunosorbentsIBA 04/2017 - 07/2014
2	Peptide Initiation Factors (Initiation Factor)IBA 01/2017 - 01/2016
1	tryparedoxin peroxidaseIBA 08/2022
1	quinolineIBA 07/2022
1	SaltsIBA 07/2022
1	Acarbose FDA LinkGeneric 06/2021
1	Clioquinol (Vioform)FDA Link 01/2020
1	UCON 50-HB-5100 (F127)IBA 01/2020
1	Leishmania infantum amastin proteinIBA 01/2020
1	TubulinIBA 04/2019
1	A-Form DNA (A-DNA)IBA 01/2019
1	Interleukin-2 (IL2)IBA 01/2019
1	Immunoglobulins (Immunoglobulin)IBA 01/2019
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2018
1	Adenosine Monophosphate (AMP)IBA 03/2018
1	ProteomeIBA 01/2018
1	DNA (Deoxyribonucleic Acid)IBA 01/2018
1	Pharmaceutical PreparationsIBA 01/2018
1	Glutamine (L-Glutamine)FDA Link 11/2017
1	Phosphopyruvate Hydratase (Enolase)IBA 07/2017
1	Poloxamer (Poloxamer 407)IBA 10/2016
1	Oxyquinoline (8 Hydroxyquinoline)FDA Link 02/2016
1	Immunoglobulin E (IgE)IBA 01/2016
1	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 01/2016
1	Translationally-Controlled 1 Tumor ProteinIBA 01/2016
1	PolyproteinsIBA 01/2016
1	N 30IBA 01/2016
1	Immunologic Factors (Immunomodulators)IBA 02/2015
1	CholesterolIBA 02/2015
1	SphingomyelinsIBA 02/2015
1	Mitogen-Activated Protein Kinase 3IBA 02/2015
1	Mitogen-Activated Protein KinasesIBA 02/2015
1	Cathepsin LIBA 01/2015
1	Surface Antigens (Surface Antigen)IBA 01/2015
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 07/2014
1	PeroxiredoxinsIBA 01/2014
1	Interferon-gamma (Interferon, gamma)IBA 07/2013
1	Messenger RNA (mRNA)IBA 07/2013
1	Interleukin-8 (Interleukin 8)IBA 01/2012
1	Transcription Factors (Transcription Factor)IBA 04/2011

Therapy/Procedure

2	Therapeutics 02/2022 - 12/2016
1	Precision Medicine 04/2019
1	Euthanasia (Mercy Killing) 01/2018